مشخصات کلی Clinical manifestations and diagnosis of acromegaly

نویسنده کتاب (Author):

Lugo, Gloria; Pena, Lara; Cordido Carballido, Fernando

انتشارات (Publisher):

Hindawi 2012

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

lugo-g-pena-l-cordido-f-clinical-manifestations-and-diagnosis-of-acromegaly-int-j-endocrinol-2012201210p

توضیحات خلاصه (Summary):

[Abstract] Acromegaly and gigantism are due to excess GH production, usually as a result of a pituitary adenoma. The incidence of acromegaly is 5 cases per million per year and the prevalence is 60 cases per million. Clinical manifestations in each patient depend on the levels of GH and IGF-I, age, tumor size, and the delay in diagnosis. Manifestations of acromegaly are varied and include acral and soft tissue overgrowth, joint pain, diabetes mellitus, hypertension, and heart and respiratory failure. Acromegaly is a disabling disease that is associated with increased morbidity and reduced life expectancy. The diagnosis is based primarily on clinical features and confirmed by measuring GH levels after oral glucose loading and the estimation of IGF-I. It has been suggested that the rate of mortality in patients with acromegaly is correlated with the degree of control of GH. Adequately treated, the relative mortality risk can be markedly reduced towards normal.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Lugo, Gloria; Pena, Lara; Cordido Carballido, Fernando

شناسه OCLC:979265424

Language Note:English

فهرست محتوا:1687-8345 1687-8337 http://hdl.handle.net/2183/18065

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